Drawings that went into the Dermal Regeneration Template info-doodle~
Background: DRT or Integra?
The most common brand name of DRT is Integra, and that’s what most people will call a DRT. However, I’m not here to rep a brand specifically, so I’m going to try to avoid referring to the technology by brand name unless it’s specifically called for.
Wound healing tech doodles!
Without further ado:
My drawing of the DRT mesh. It’s made of collagen. The holes make it more pliable.
I drew the view in the microscope. Your own cells colonize the scaffold.
A cartoon sort of rendition of the collagen fibers and how your fibroblasts know just what to do with collagen: Hug it and get to growing.
This is what it looked like with the surgeon holding the dermal regeneration template sheet. It would momentarily be lain on the wound bed.
There seem to be a few different varieties of acellular, created tissue that they can lay as a scaffold for healing.
It looked like the doctor was unpackaging American cheese. Was it cheese? No.
A short history of tissue engineering, especially the types of tissue engineering we use in phalloplasty and trans bottom surgery
Left: The essence of how a dermal regeneration template works, especially for deep full thickness grafts. Right: A simplification of split thickness scar adhesion to a deep wound bed. (Potential bias alert since it wouldn’t be like this for all phalloplasty donor sites)
I got to learning about skin & drew a chunk. On the poster I labeled all the elements.
Simplified depiction of the process of scar contraction vs colonization via dermal regeneration template. (Top two rows) Donor site inflammation and scar contracture; (Bottom two rows) DRT implantation preventing scar contracture and reducing inflammation. Potential bias due to simplification.
This is neat— a DRT allows the circulation to start returning before your cells have colonized and replaced the collagen. It also looks like a sheet cake.
A wound healing timeline from surgery to healed. The stages of healing. How a DRT (maybe Integra) fits into that timeline vs direct grafting.
I drew scar pliability. Where there are adhesions, you won’t have as easy a time just pinching a bit of skin. It will seem sort of stuck down to itself and won’t want to move. A DRT often helps with scar pliability, since it guides the matrix of healing to follow an organized pattern.
Hope that helps you get some info you needed. Remember, as a brand, Integra is so commonly used that it’s like Kleenex or Xerox. The technology is really called a dermal regeneration template : )